Special breeding techniques for use in mouse mutation analysis

VE Papaioannou, RR Behringer - Cold Spring Harbor …, 2024 - cshprotocols.cshlp.org
genetic interactions are detailed here for gene families, in which there may be redundancy
or genetic compensation of different genes, for genes … Martin) “cheating Mendel” because the …

Satellite DNA-mediated diversification of a sex-ratio meiotic drive gene family in Drosophila

CA Muirhead, DC Presgraves - Nature Ecology & Evolution, 2021 - nature.com
… If sufficiently common, these arms races may have important consequences for the evolution
of stable Mendelian transmission, gametogenesis, recombination rates, genome structure, …

Bypassing Mendel's First Law: Transmission Ratio Distortion in Mammals

G Friocourt, A Perrin, PA Saunders… - International Journal of …, 2023 - mdpi.com
… for almost a century, primarily because it cheats Mendel’s first law: males … gene called
SmokTcr was isolated in 1999 [48]. It is part of the sperm motility kinase (Smok) multi-gene family

A Chronicle on Genetics and the March of Darwinian and Mendelian Medicine

DR Govindaraju - 2020 - Springer
… The film also hints at the need for taking a unified Darwinian-Mendelian and Hippocratic
approach toward building a healthier human society. In short, this is a beautiful and engrossing …

Meiotic drive in house mice: mechanisms, consequences, and insights for human biology

UP Arora, BL Dumont - Chromosome Research, 2022 - Springer
… into how drive elements cheat the rules of Mendelian inheritance. Beyond these technical …
used to identify and characterize loci that defy Mendelian segregation. We then profile several …

[HTML][HTML] No Mendelian genes in psychiatry?

JV Pardo - Journal of Psychiatry and Brain Science, 2021 - jpbs.hapres.com
To date, no gene following Mendelian inheritance (eg, monogenic variant) has been
discovered for any common psychiatric disorder. This unfortunate circumstance has delayed …

Proteome-wide mendelian randomization identifies causal plasma proteins in venous thromboembolism development

H Li, Z Zhang, Y Qiu, H Weng, S Yuan… - Journal of Human …, 2023 - nature.com
… Of these 13 proteins demonstrated Mendelian randomized correlations. Six proteins (F2, F11,
PLEK… key hints for future research and possible diagnostic and therapeutic targets for VTE. …

Charles Darwin versus Gregor Mendel

K Binmore, K Binmore - … Dialogues: between Sages down the Ages, 2021 - Springer
… It seems out of character for Mendel to have deliberately cheated like Millikan. The explanation
offered that seems most likely to me is that when the data deviated from his predictions …

Assessing causal relationships between gut microbiota and psoriasis: evidence from two sample Mendelian randomization analysis

Y Li, G Chen, X Hu, Y Bao, C Wu, N Zeng, F Jiang - Scientific Reports, 2024 - nature.com
… Mounting data hints that the gut microbiota's role may be pivotal in understanding the emergence
… In this exploration, we adopted a Mendelian randomization (MR) strategy to probe the …

Genetic conflict and the origin of multigene families: implications for sex chromosome evolution

E Martí, AM Larracuente - Proceedings of the Royal …, 2023 - royalsocietypublishing.org
… of ploidy and fair Mendelian segregation of chromosomes during … genes (out of 35, if we
consider the ampliconic gene family in the … Here the cheaters tend to involve repetitive DNAs at …